I'd think long and hard about it at least.
But one of the first things I'm thinking is that we're coming off a (Denver) game where our lack of depth (because of injuries/ejection in this case) almost lost us the game. We almost were not able to pull things off, having to rely on Udoh, Allen and Niang.
This proposal means that (at least without finding stuff in the buyout market this season, or the cheap FA market next season), we'd be relying on Udoh as the number 2 center, Neto as the number 2 PG, and Niang as the #3 PF. That might be expecting too much from them, not to mention that any injuries (esp. at PG or C) would leave us very vulnerable.
I'd also be thinking that we now would be at a distinct disadvantage when teams go with two bigs on us (Locke was mentioning that Denver's statistically best lineup includes both Jokic and Plumlee, for example). Though I think Crowder and Porter could handle the PF spot most of the time, they are overmatched because of height or weight (respectively) on occasion (having Ingles and O'Neale as emergency PF depth doesn't solve the problem). We might survive with the small-ball pressure we'd be putting on them, but it's risky losing functional depth.