RandyForRubio
Well-Known Member
Isn't it cause your chromosomes keep on replicating, and basically the older you get the higher chance that they screw up? Laymens terms, I know. Or am I way off base?! Thanks doc!
The Cure for Cancer. (the dumbed down version)
- Thread starter Hotdog
- Start date
Isn't it cause your chromosomes keep on replicating, and basically the older you get the higher chance that they screw up? Laymens terms, I know. Or am I way off base?! Thanks doc!
Zulu
Well-Known Member
Yes, Everytime one of your cells replicate your genome you have a chance of getting a mutation, so the older you are the more times your cells have replicated and therefore the more chances at getting a mutation. Or speed up the process and add a few carcinoges!!!
In the 70s, sitting in science/medical libraries reading cancer research papers then, I found anecdotal reports of patients who recovered dramatically from cancer while fighting off, immunologically, infectious diseases. Doctors were going "OMG, we're not going to get to kill the patient with chemo because the toxic puss will kill him first." It was either a paranoid panic in the minds of the doctors at the shock of being upstaged by nature, or some astute thinking researcher curiously wondering how the immune system can clean up a hopeless cancer so much better than our mutagenic nucleoside derivatives and other poison chemo agents. . . . . not sure which. . . . .
Doublea
Well-Known Member
I'm a biotechnology major at school and we tested for it using high res melting in one of my classes. My ancestry is european mainly from England and Wales. My professor was pretty excited because I was like only the 3rd person she's taught to be homozygous.
Zulu
Well-Known Member
Very cool, what school was this at?
Doublea
Well-Known Member
UVU, just getting my bachelors and trying to figure out what I want to do with my life...
Doublea
Well-Known Member
Archie Moses
Well-Known Member
I didn't want to make my own thread so decided to post this in here. In the OKC Game thread, there have been talks of passing kidney stones and I guess, I wanted to share something that's been in my mind.
Last December I went to the ER with what I thought was a kidney stone. I passed one four months earlier and four before that. I usually have a very different experience when passing them than most people do. The first sign is usually having blood in my urine, but no pain. After about week after that, my prostate area starts to feel uncomfortable for a few weeks and then the pain slowly goes away. It's not extreme pain, but it ****s with you. Then, usually, out of no where I'll pass the stone and it doesn't really hurt at all.
Last December was completely different. I had extreme pain in my lower left abdominal area and I wanted to die. I almost passed out a few times and the pain was so bad it made me nauseous. When I went to the ER they made me do a CT scan. They told me I had a few small stones in my kidneys and the one I thought I was passing had more than likely passed and was just the size of a grain of sand. I was never given a report of this CT scan.
Since last December I've had a lot of weakness and pain in my left hip. I've gone to my doctors and complained to them, but they just kept referring me to other doctors who would do the same thing. They all thought my hip pain was because of my chronic back pain and being out of alignment or kidney stones. I got referred all the way to a pain psychologist because no one would help me and made me feel like it wasn't that bad or between my ears. There have been 4 doctors I've gone to about my hip this past year and not one of them did any imaging or tests of my hip.
About a month ago I felt like I was passing a stone again. I had pain in my abdominal area and prostate area and my hip. I was referred to a urologist who I met and he immediately ordered a CT scan. This was done about two weeks ago now. I got the report back from my CT scan and there was no stone like last December. However, this dr/radiologist compared my CT scan to the year before and found a lesion 6cm by 2cm in my left hip. It was in my last CT scan from last December as well and the same size - but no one ever caught it then. The dr. thinks it could be something called Padget's Disease, or some sort of bone cyst form a bone disease or bone cancer. The good news is it hasn't grown at all in a year. I'm frustrated they didn't catch this a year ago when they did the first CT scan cause it showed up on it - and I'm frustrated none of the docs I've been to about my hip pain caught it too. Chronic pain is a bitch to deal with.
I have an ink injection bone scan and MRI scheduled for the 5th. I'm hoping, obviously, it turns out to be nothing or something treatable. It's hard not to think about it though and I have a million thoughts racing through my head and sometimes I can't sleep. At the end of the day, I would just like to know what it is rather than not know.
This is just a jist of the whole story though. Our medical system, to me, can be an absolute joke.
Last December I went to the ER with what I thought was a kidney stone. I passed one four months earlier and four before that. I usually have a very different experience when passing them than most people do. The first sign is usually having blood in my urine, but no pain. After about week after that, my prostate area starts to feel uncomfortable for a few weeks and then the pain slowly goes away. It's not extreme pain, but it ****s with you. Then, usually, out of no where I'll pass the stone and it doesn't really hurt at all.
Last December was completely different. I had extreme pain in my lower left abdominal area and I wanted to die. I almost passed out a few times and the pain was so bad it made me nauseous. When I went to the ER they made me do a CT scan. They told me I had a few small stones in my kidneys and the one I thought I was passing had more than likely passed and was just the size of a grain of sand. I was never given a report of this CT scan.
Since last December I've had a lot of weakness and pain in my left hip. I've gone to my doctors and complained to them, but they just kept referring me to other doctors who would do the same thing. They all thought my hip pain was because of my chronic back pain and being out of alignment or kidney stones. I got referred all the way to a pain psychologist because no one would help me and made me feel like it wasn't that bad or between my ears. There have been 4 doctors I've gone to about my hip this past year and not one of them did any imaging or tests of my hip.
About a month ago I felt like I was passing a stone again. I had pain in my abdominal area and prostate area and my hip. I was referred to a urologist who I met and he immediately ordered a CT scan. This was done about two weeks ago now. I got the report back from my CT scan and there was no stone like last December. However, this dr/radiologist compared my CT scan to the year before and found a lesion 6cm by 2cm in my left hip. It was in my last CT scan from last December as well and the same size - but no one ever caught it then. The dr. thinks it could be something called Padget's Disease, or some sort of bone cyst form a bone disease or bone cancer. The good news is it hasn't grown at all in a year. I'm frustrated they didn't catch this a year ago when they did the first CT scan cause it showed up on it - and I'm frustrated none of the docs I've been to about my hip pain caught it too. Chronic pain is a bitch to deal with.
I have an ink injection bone scan and MRI scheduled for the 5th. I'm hoping, obviously, it turns out to be nothing or something treatable. It's hard not to think about it though and I have a million thoughts racing through my head and sometimes I can't sleep. At the end of the day, I would just like to know what it is rather than not know.
This is just a jist of the whole story though. Our medical system, to me, can be an absolute joke.
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I'm sorry about your experience, Archie.
My wife has needed some help and we couldn't seem to get any help.. no one seemed to give a ****.
Her symptoms went on for years.
I finally found a doc in Las Vegas that took the care and within 30 days had all but cured all of her chronic symptoms.
I hope you find the same and that whatever is the cause of your pain is easily curable.
Keep in touch (though I never come around here any more).
Archie Moses
Well-Known Member
Thanks, Doc.
I felt kind of dumb after I posted this - like, what was the point even?!?! I guess, getting it off my chest was something I needed, regardless if it's to random people on a Jazz forum. I haven't even told most of my family cause I don't want them worrying like I've been.
I'm glad your wife found the help she needed. In my experience, I've had so many poor experiences with docs it made me want to never go see another one again. I know there are great docs out there, but damn, the ones I run into brush you off and charge my insurance company and myself up bizarre amounts of money. I had a doc appointment last month that charged my insurance company 500+ bucks for an appointment they made with me where I showed up and the doc sat down with me for five minutes and told me his plan was to get me into physical therapy and to see a pain psychologist. **** a secretary could have easily done on the phone. I took work off, drove an hour to the appointment and left unbelievably pissed. What a joke.
I completely agree. I know these folks have a ton of education and probably in certain situations are very very valuable, but anytime I've had something I wanted to better understand they show almost no interest in finding out what's really going on and just want to prescribe antibiotics and send me on my way. Or some variation of that. They aren't really trying to give me customized care, they just want to tick off all the checkboxes and do the standard thing and move on to the next patient.
I've lost 50lbs since May, and eventually I went to a doctor because I have high blood pressure and because I wanted to make sure my diet and exercise was okay. The guy doesn't have time for me to explain my weight loss plan, my exercise routine, my short and mid-range goals, what I should do to get there, etc.. I asked how I could get an accurate body fat percentage and he basically said there really isn't a way to do that and blew it off. Once I reach my phase 1 goal I'm not going to be as concerned with weight loss. Phase 2 is going to be about getting to a certain body fat percentage. BMI is a joke and I have no desire to weigh what it says I should weigh. I've been anywhere from 135lbs to 265lbs in my adult life and I know I don't want to weigh less than 160, but that's basically the very upper limit of what BMI says my healthy weight is and that 140s is healthy. I know from my semi-annual physical readiness test in the Navy I pretty much need to be anorexic to make BMI but I have no problem passing the neck:waist test.
It's funny there are disclaimers telling you to check with a doctor before starting diet and/or exercise routines, like they are going to give you specific advice other than "Yeah, exercise and eat better, duh."
The Thriller
Well-Known Member
Isn’t Dala’s work in his lab kinda blow up the GOP’s anti-single payer system rhetoric that single payer systems inhibit innovation?
Keep up the good work!
Wow.
I was working on cancer research for almost twenty years, nearly 50 to 30 years ago. Doing lab work, extracting current results from research publications for reference in papers being composed. All kinds of stuff.
impressive to see such a fine group of currently involved folks in here.
I left with a conviction that our immune systems were by the far the superior tool to resort to. Saw lots of weird reports about patients beyond hope getting some damn infectious or viral killer too. Docs thought they were goners for sure. But somehow, some immune trigger got turned on, and cleaned out both problems.
Kind of like my own bizarre medical phenomena in 1975. Docs thought I was so hopeless they didn't even prescribe aspirin..... I have to thank God, or my immune system. Well, both.
way back when, I also realized that cancer is such a personal thing..... even in the pure biochemistry of the thing.... that we would eventually have to actually have the technology of making specific determinations on the patient to effectively treat the patient. Long way off.
Back then, researchers were looking for a magic bullet that would constitute a universal "Cure". And a Nobel Prize. Whatever progress we have made has been limited to specific cases or case types, with only statistical "victories" as measured against doing nothing. With draconian painful treatments that give hope for less than a 20% chance of extending life, on immensely painful terms, for a year or so..... costing a million dollars or so.....
I determined I would not ever do chemo......on any terms...... after seeing my boss die from cancer after being involved in the launching of many chemo agents....
I was working on cancer research for almost twenty years, nearly 50 to 30 years ago. Doing lab work, extracting current results from research publications for reference in papers being composed. All kinds of stuff.
impressive to see such a fine group of currently involved folks in here.
I left with a conviction that our immune systems were by the far the superior tool to resort to. Saw lots of weird reports about patients beyond hope getting some damn infectious or viral killer too. Docs thought they were goners for sure. But somehow, some immune trigger got turned on, and cleaned out both problems.
Kind of like my own bizarre medical phenomena in 1975. Docs thought I was so hopeless they didn't even prescribe aspirin..... I have to thank God, or my immune system. Well, both.
way back when, I also realized that cancer is such a personal thing..... even in the pure biochemistry of the thing.... that we would eventually have to actually have the technology of making specific determinations on the patient to effectively treat the patient. Long way off.
Back then, researchers were looking for a magic bullet that would constitute a universal "Cure". And a Nobel Prize. Whatever progress we have made has been limited to specific cases or case types, with only statistical "victories" as measured against doing nothing. With draconian painful treatments that give hope for less than a 20% chance of extending life, on immensely painful terms, for a year or so..... costing a million dollars or so.....
I determined I would not ever do chemo......on any terms...... after seeing my boss die from cancer after being involved in the launching of many chemo agents....
Look, no reason to be sensitive to some folks who really won't understand any explanation. Humor is a small placebo for big thoughts. Innocent fun where for whatever reason real benefit is beyond reach.
So I've never heard of this mutation. Besides an obvious benefit for survival in some respects, what else is involved? I'm sure even HIV, small pox, and the plague are not strong enough threats to survival to make CCDR5 Delta 32 a requirement for survival or positive selection..... but surely there is some positive value to it overall.....
What symptoms? My wife has been having issues for years as well and all that gets done is throwing drugs at it that don't fix anything, just mask the problem or make her numb to it.
One thing I’ve learned with doctors is that in most cases, you have to be very pushy to get them to do more than the bare minimum. I don’t know if it’s because they’re so busy, trying to cram as many patients in one day as possible, or because of the current doctor/insurance/patient relationship. Probably both.
Archie Moses
Well-Known Member
I showed up for my appointments today and after paying $1,500 to reach my deductible, I get taken back for the nuclear injections for the bone scan. While walking with the tech, she informs me my MRI was cancelled by my insurance today, but didn't know why. She does the injection and basically we watch how my blood is flowing in my lower abdominal area and hip. You could see the blood in my kidneys and a great outline of my junk. Lol. I have to go back in at 1 PM for the rest of the bone scan and called my insurance to see why they cancelled my MRI last second, without informing me. Basically, I was told that they need one of the insurance doctors to talk my doctor who ordered the MRI about why I need an MRI and then if he/she deems it worthy, I can have the MRI. What a joke. I'm sure this will take another month...
Good luck, Archie, with your testing today. I hope they can find out what is wrong and a way to treat it that will take care of the problem.
I have had entirely too much experience with having doctors not listen or seem to care about symptoms that they cannot easily pin to an illness. It is hard to find a doctor who will go the extra mile, who might consider that there is an alternative to what they already know. I can see how being a doctor can make one pretty arrogant, or maybe it is arrogant people that become doctors, but on occasion you find one who likes to solve the mystery instead of believing that they know all there is to know. All you can do is be your own advocate and fight for yourself.
And I totally get why you told your story here before telling other people in your life. I did the same thing. I needed to tell the story, but I also needed to not have people who love me freak out about it right away. So telling a group of people who are not quite strangers but also not emotionally invested in you is therapeutic.
I have had entirely too much experience with having doctors not listen or seem to care about symptoms that they cannot easily pin to an illness. It is hard to find a doctor who will go the extra mile, who might consider that there is an alternative to what they already know. I can see how being a doctor can make one pretty arrogant, or maybe it is arrogant people that become doctors, but on occasion you find one who likes to solve the mystery instead of believing that they know all there is to know. All you can do is be your own advocate and fight for yourself.
And I totally get why you told your story here before telling other people in your life. I did the same thing. I needed to tell the story, but I also needed to not have people who love me freak out about it right away. So telling a group of people who are not quite strangers but also not emotionally invested in you is therapeutic.
suri1100134
New Member
it's a joke huh?