PearlWatson
Well-Known Member
A simplification? Those statements say completely different things. Your 'simplifications' are misleading, and I'm sure this isn't the only one. If your 'debate purposes' are misleading other readers in this forum, perhaps you should reconsider what your 'purpose' with your involvement in this thread truly is.
Yes, but think deeper. This translocation is more like "one and 30% of a laminated page (if we assume that the gene is in an imprinted area, and therefore the DNA is methylated) being thrown 40 pages ahead into a chapter in the book with pages made of papyrus".
There is simply so much variation in the mere structure of the nucleic acid backbone within a single chromosome-- let alone between chromosomes. Moving half of a gene from chromosome 14 to 8 in the middle of another gene begets new start and stop transcription sites, which can create novel genes-- which, of course, can be beneficial or detrimental. Translocations are in no way intrinsically deleterious.
Please stop it with the simplifications. They both inhibit your understanding of the science, as well as the other readers of this thread.
None of the details you added have contradicted my point that in any of these instances (duplication, translocation, recombinant) no new information is added.
You have more information and rearranged information but not new.
Jerry Bergman, Ph.D., Biology: "The adverse effects of gene duplication, such as Down’s syndrome, are well known. Although the methodology is available, evidence of functionally useful genes as a result of duplication is yet to be documented."