The press for some reason needs to make this a good guy v. bad guy thing but the fact is more like bad guy vs. bad guy - Pacquiao's a degenerate gambler (rumor is he's broke), openly cheats on his wife and uses his platform in the Filipino House of Representatives to spew anti-gay hate speech.
As far as juicing is concerned he's never failed a test but neither has Barry Bonds. All I can say is he started out fighting at 110 pounds and now he fights (on fight night) somewhere in the neighborhood of 160 pounds. How does an adult male start at 110, put on 50 pounds and still maintain world class conditioning? Not saying it's impossible but at some point common sense has to take over.
As far is the fight is concerned Manny doesn't stand a chance. I've watched Floyd's last 7 or 8 fights (at least) and he's dominated every one - the SD to De La Hoya and his two recent MD's were all jokes - he's clearly won every fight. Yes it would have been a better fight 5 years ago but Floyd would have beaten him then too.