I think Denver's OLine is more due to Payton Manning's ability to work in the pocket, read defenses, and no one gets rid of the ball quicker. Regardless of whether he played for Denver or Indianapolis. He never got sacked much.
That is also true and plays into Denvers favor. The O-Line has been fantastic for Peyton. The speed with which he reads defenses and gets rid of the ball only magnify that. This is a good advantage for Denver.
I am most worried about Wilson getting out of the pocket and making plays with his arm and feet. If he does that I think he can break down the Denver D.
Even if they don't pass to Shermans' man very often that is fine. You still have 3 of Decker, Thomas, Welker and Thomas making big plays. Plus Denver is a league best in yards after catch with 2,751 yards after the catch this season.